The Story Behind Hyperpigmentation
Hyperpigmentation is an excess quantity of pigment, triggered by an internal or external cause. Hyperpigmentation can be particularly stubborn to treat.
This article covers several points:
- What is normal pigmentation
- What is hyperpigmentation
- Where does it come from.
- I'll also list the three different types of hyperpigmentation and the methods to treat and control hyperpigmentation.
Normal Pigmentation Function
Pigmentation in the human skin 1 protects us against UV radiation, it acts as a own multi-SPF. Protecting your skin cells from radiation damage, by absorbing the UV rays.
Unfortunately, they can only absorb so much, then the process breaks down, leading to hyperpigmentation and possibly skin cancer.
Let’s example the three layers of skin to see where pigmentation, or color comes from.
The Epidermis - The epidermis, consisting of two layers.
¨ The top layer, the Stratum Corneum contain layers and layers of dead cells
¨ The bottom layer of the epidermis is alive.
There at the base of the bottom layer of the epidermis exist a wavy border
Bingo,,,, This is where the color factory begins.
Where does pigmentation come from?
The wavy layer between the dermis and live layer of the epidermis, your 2epithelial cells are born and the melanocytes cells also exist in this wavy border.
These melanocytes sprinkle melanin, melanin, which is the pigment that gives skin its color, into the new epithelial cells as they come into existence. Melanin is the natural pigment in your skin. Each cell is given a dose according to your generic programing, in other words your “Fitzpatrick Skin Type” . More information below on Skin Fitzpatrick Scale .
The Role of Epithelial Cells Plays In Producing Even Skin Tones
As each epithelial cell is born it absorbs the melanin give it by the melanocytes and starts its migration to the surface carrying its bounty of nutrients and melanin. Each generation as it’s being born moves the previous generation upward. Bringing with its allotted amount of pigment.
If nature is undisturbed everything works according to plan. We have even skin tones, no dark spots or hyperpigmentation. But, that’s not the case, is it?
What is hyperpigmentation and the causes?
Hyperpigmentation presents itself in 3,4 different ways. Listed below are the three types of hyperpigmentation. .
Age Spots, Lentigines, Liver Spots
The most common cause is due to long term UV exposure without sun protection. Overexposure to the sun is a common cause of hyperpigmentation, the leading cause of dark spots in light-skinned individuals.
Lentigines usually come more widespread with age. 90% of light-skinned people over the age of 60, Lentigines are not caused by the aging process, but linked to ultra violet radiation exposure.
Protect your skin from UV radiation. We’re exposed to UV rays every day despite how bright the sun is shining. You should use beauty products that contain SPF protection. Moisturizers, lip balm, lipstick, makeup and don’t forget your sunscreen.
Melasma or Pregnancy Mask
Melasma is the excess of pigment in areas, such as the cheeks,temples or forehead. Why does 5melasma happen? Melasma is in your genes it could be hormonal and UV induced or possibly triggered by phototoxic medications.
Hormonal in balance can trigger melasma. The rise and fall of hormones during pregnancy, thyroid dysfunction, hormone replacement therapy or with birth control pills are possible causes.
Melasma is a very difficult condition to treat. It affects about five to six million women in the United States. A patchy brown discoloration that occurs on sun-exposed areas on the face and is frequently referred to as the “mask of pregnancy” because it often happens during pregnancy. Melasma can materialize in anyone, although the disorder is more common in the Fitzpatrick IV skin.
Sun exposure also can worsen melasma. According to dermatologist’s recommendations, sunscreen should be applied every two hours and wearing a wide-brimmed hat for extra protection.,
Melasma pigmentation can be reduced certain lasers, chemical peels and melanin suppressants.
Post-inflammatory Hyperpigmentation (PIH)
The injury or trauma to the skin produces inflammation. This inflammation causes the melanocytes cells to produce extra melanin . Post-inflammatory hyperpigmentation is most common in people with darker skin tones.
This type of hyperpigmentation usually follows skin injuries, such as, acne injuries, psoriasis, burns, manual friction or the wrong chemical peel.
Other possible causes of hyperpigmentation
- Certain prescription medications make the skin photosensitive, resulting in hyperpigmentation.
- In addition, some illnesses could cause hyperpigmentation.
- Hyperpigmentation and driving - UV exposure is 5 times greater to the left arm and 20 times greater to the left side of the face. This left-side sun exposure triggers sun damage, wrinkles, skin leathering, sagging, hyperpigmentation and age spots. The more time you spend driving, the higher your risk of sun related skin damage.
Ethnic Skin & Hyperpigmentation
Ethnic skin has an increase melanin in their skin and the 4melanocytes the cells that make the pigment are very sensitive to trauma. Consequently, any minor injury, such as picking a blemish or an insect bite could develop into a long-lasting or permanent dark spot.
The major of Post Inflammatory Hyperpigmentation is the results of the additional melanin produced in people of color, which includes African, Asian, Hispanic, Middle Eastern, Native American and Pacific Island heritage see (Skin Fitzpatrick Scale) below.
Inflammation produces extra pigment, The melanin produced during an inflammatory injury can enter the dermis. These cells can stay in the upper dermis for a long period. That includes wearing sunscreen. Darker-skinned people are not immune to sun damage. Even though high levels of melanin exist, it does not give 100% protection from the sun’s UV radiation.
In fact, it’s the same melanin levels, that causes darker-skinned people to develop dark spots easily. That’s why reducing hyperpigmentation should be a slow process. It’s important not stimulate the melanocytes into producing additional melanin. The skin needs time to regenerate itself, this process could take months depending on cell turnover. Steps should be taken as to not cause additional inflammation or injury.
Fitzpatrick Skin Scale
photograph courtesy of the Researchgate
How long does it take to get rid of hyperpigmentation?
"Epidermal hypermelanosis will appear tan, brown, or dark brown and may take months to years to resolve without treatment".
To accelerate the brightening process, introduce melanin suppressants into your home care treatment as well as professional treatments.
Products must be used morning and evening for a minimum of 8 weeks before an improvement in the skin is noticed. Patches may actually look darker before they look lighter because of the speeding up of the desquamation (shedding) process.
If the injury is not repeated and the area is protected from direct sun light, the dark spot will begin to fade on its own as the skin renews itself - this process could take months or more.
First and above all else, you HAVE to protect the area from UV radiation. Wearing good sunscreen protection is a must. Use a hat and stay out of direct sunlight as much as possible. This will allow the melanocytes cells to calm down and work less aggressively.
How do you treat hyperpigmentation?
There are many combinations of treatments available to treat PIH safely and effectively. When treating epidermal PIH the best products for hyperpigmentation are topicals 6,7depigmenting agents, such as the following ingredients:
These depigmenting topicals can be effective by themselves or synergistically. Chemical peels, such as salicylic acid, glycolic acid, Jessner's and Trichloracetic acid (TCA) peels can be combined with topicals as part of a PIH treatment program for deeper pigmention problems.
Studies have shown laser therapy is beneficial, particularly the Q-switched ND:YAG.
In addition to depigmenting topicals, there are quite a few cosmeceutical ingredients that can be added to enhance your results. I’ve listed thirteen in my article 13 Skincare Ingredients To Reduce Hyperpigmentation, but there are many more available in today’s market.
Start with a good skin care routine
First of all a GOOD sun protection is a must. It’s very important to minimize the effects’ of the sun UV’s rays being absorbed by your skin’s cells.
Your skincare regime should include natural melanin inhibitors to lower the amount of melanin distributed into the skin.
Then, once the skin starts responding, it’s ready for a gentle exfoliation. The exfoliation should be very gentle, steady, but effective to rid the skin of pigmentation and restore even skin tones.
In order to keep the results you must remain on a good skincare regime.
One that should include retiniol (vitamin A) for normalizing celllular turnover, vitamin C & E for anti-oxidant support. Vitamin C is a natural skin brightener.
How you treat hyperpigmentation depends on it’s root source. In addition to the individual’s skin Fitzpatrick type. Each cell is given a dose melanin according to genetic heritage.
Melasma is an acquired pigmentary disorder characterized by brownish hyperpigmented macules usually on the face.
Laser and IPL treatments of melasma are for individuals with stubborn melasma who failed with topical treatments or a series of chemical peels.
The persistent and stubborn characteristics of melasma make it difficult for treatment. Choosing the right laser and the correct settings is vital in the treatment of melasma.
According to Asher Milgrom, PhD – AMA’s CEO and Chief Scientist, “The trick is knowing what kind of energy to use, or combination of energies to use that are emitted from different lasers.
As a matter of fact, there are 5 different frequencies of laser energy that are useful in targeting melanin. Furthermore, there are 3 different ways to modulate the “pulse duration” of the energies that also affect how the melanin will interact with the laser (Long-Pulse, Q Switched, PICO).”
Studies of laser– IPL treatments for individuals with melasma have shown that a maintenance routine after treatment is necessary to slow the recurrence of melasma.